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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of proliferative vitreoretinopathy (PVR)
ncRNA name PKCα siRNA
ncRNA Category siRNA
Disease name proliferative vitreoretinopathy (PVR)
Species Mus musculus
Tissues/Cell_line retinas
Methods siRNA injection, RT-PCR, Western blot, immunofluorescence
Expression pattern associated
Functional description Gene therapy with siRNA-PKCα could effectively inhibit PVR in mice and provide us with a novel therapeutic target on PVR.
PubMed ID 23626468
Year 2013
Title The inhibitory effect of small interference RNA protein kinase C-alpha on the experimental proliferative vitreoretinopathy induced by dispase in mice.
Drug-related ncRNA NO

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